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Name | Cannabinoid receptor 2 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Cnr2 |
Synonym | Peripheral cannabinoid receptor mCB2 CB2-R CB2 receptor CB2 [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 347 |
Amino acid sequence | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT |
UniProt | P47936 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5373 |
IUPHAR | 57 |
DrugBank | N/A |
Name | CHEMBL2348465 |
---|---|
Molecular formula | C28H38O3 |
IUPAC name | (6aR,9R,10aR)-3-(1-adamantyl)-9-[(Z)-2-methoxyethenyl]-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol |
Molecular weight | 422.609 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 1 |
XlogP | 7.4 |
Synonyms | BDBM50432724 |
Inchi Key | BDARCOUKTBOYTA-XQJOSDQISA-N |
Inchi ID | InChI=1S/C28H38O3/c1-27(2)23-5-4-17(6-7-30-3)11-22(23)26-24(29)12-21(13-25(26)31-27)28-14-18-8-19(15-28)10-20(9-18)16-28/h6-7,12-13,17-20,22-23,29H,4-5,8-11,14-16H2,1-3H3/b7-6-/t17-,18?,19?,20?,22+,23+,28?/m0/s1 |
PubChem CID | 71661887 |
ChEMBL | CHEMBL2348465 |
IUPHAR | N/A |
BindingDB | 50432724 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 90.0 nM | PMID23621789 | BindingDB |
Ki | 90.3 nM | PMID23621789 | ChEMBL |
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