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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701944
Molecular formula	C17H19BrN2O
IUPAC name	N-[(4-bromophenyl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	347.256
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.3
Synonyms	US8802673, 45 BDBM129403 SCHEMBL12609923
Inchi Key	MGTDIWDRSWFSMH-QGZVFWFLSA-N
Inchi ID	InChI=1S/C17H19BrN2O/c18-15-5-1-13(2-6-15)11-20-16-7-3-14(4-8-16)17-12-19-9-10-21-17/h1-8,17,19-20H,9-12H2/t17-/m1/s1
PubChem CID	68325657
ChEMBL	CHEMBL3701944
IUPHAR	N/A
BindingDB	129403
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	6.1 nM	, None	BindingDB,ChEMBL

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