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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(3) dopamine receptor
Species	Chlorocebus aethiops (Green monkey)
Gene	DRD3
Synonym	Dopamine D3 receptor
Disease	N/A for non-human GPCRs
Length	400
Amino acid sequence	MAPLSQLSGHLNYTCGVENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRVCCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVTLMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDRAHLELKRYYSICQDTALGGPGFQERGGELKREERTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
UniProt	P52703
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2304406
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL147731
Molecular formula	C22H22N2
IUPAC name	4-phenyl-1-[(1-phenylpyrrol-3-yl)methyl]-3,6-dihydro-2H-pyridine
Molecular weight	314.432
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	4.0
Synonyms	4-Phenyl-1-(1-phenyl-1H-pyrrol-3-ylmethyl)-1,2,3,6-tetrahydro-pyridine BDBM50048237 4-Phenyl-1-[(1-phenyl-1H-pyrrol-3-yl)methyl]-1,2,3,6-tetrahydropyridine
Inchi Key	LYPHIBLOFUSFAM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22N2/c1-3-7-20(8-4-1)21-12-14-23(15-13-21)17-19-11-16-24(18-19)22-9-5-2-6-10-22/h1-12,16,18H,13-15,17H2
PubChem CID	10543298
ChEMBL	CHEMBL147731
IUPHAR	N/A
BindingDB	50048237
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	15.0 nM	PMID8523409	BindingDB,ChEMBL

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