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Name | G-protein coupled receptor 35 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Gpr35 |
Synonym | G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor |
Disease | N/A for non-human GPCRs |
Length | 307 |
Amino acid sequence | MNSTTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMHQWTETRIYMTNLAVADLCLLCSLPFVLYSLKYSSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGGFCFSSQTRRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLNTCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATSSNTPHKSQDSQILSLT |
UniProt | Q9ES90 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2390813 |
IUPHAR | 102 |
DrugBank | N/A |
Name | CHEMBL2392181 |
---|---|
Molecular formula | C20H17NO6 |
IUPAC name | 4-oxo-8-[(4-propoxybenzoyl)amino]chromene-2-carboxylic acid |
Molecular weight | 367.357 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 2 |
XlogP | 3.0 |
Synonyms | BDBM50436018 |
Inchi Key | LYGXQSMAAKFUQK-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H17NO6/c1-2-10-26-13-8-6-12(7-9-13)19(23)21-15-5-3-4-14-16(22)11-17(20(24)25)27-18(14)15/h3-9,11H,2,10H2,1H3,(H,21,23)(H,24,25) |
PubChem CID | 71733938 |
ChEMBL | CHEMBL2392181 |
IUPHAR | N/A |
BindingDB | 50436018 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 13.0 % | PMID23713606 | ChEMBL |
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