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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H3 receptor
Species	Rattus norvegicus (Rat)
Gene	Hrh3
Synonym	GPCR97 H3 receptor H3R HH3R
Disease	N/A for non-human GPCRs
Length	445
Amino acid sequence	MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
UniProt	Q9QYN8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4124
IUPHAR	264
DrugBank	N/A

Ligand

Name	CHEMBL124864
Molecular formula	C11H11BrN2O
IUPAC name	5-[2-(4-bromophenoxy)ethyl]-1H-imidazole
Molecular weight	267.126
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.6
Synonyms	4-[2-(4-Bromophenoxy)ethyl]-1H-imidazole BDBM50053277 SCHEMBL7972911 4-[2-(4-Bromo-phenoxy)-ethyl]-1H-imidazole BBXMDKJQTUCCJM-UHFFFAOYSA-N
Inchi Key	BBXMDKJQTUCCJM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H11BrN2O/c12-9-1-3-11(4-2-9)15-6-5-10-7-13-8-14-10/h1-4,7-8H,5-6H2,(H,13,14)
PubChem CID	10635514
ChEMBL	CHEMBL124864
IUPHAR	N/A
BindingDB	50053277
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	24.0 nM	PMID8809168	BindingDB,ChEMBL

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