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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neurotensin receptor type 2
Species	Rattus norvegicus (Rat)
Gene	Ntsr2
Synonym	NTRL NTR2 NT2R NT-R-2 neurotensin receptor type 2 levocabastine-sensitive neurotensin receptor High-affinity levocabastine-sensitive neurotensin receptor NTS2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	416
Amino acid sequence	METSSPWPPRPSPSAGLSLEARLGVDTRLWAKVLFTALYSLIFAFGTAGNALSVHVVLKARAGRPGRLRYHVLSLALSALLLLLVSMPMELYNFVWSHYPWVFGDLGCRGYYFVRELCAYATVLSVASLSAERCLAVCQPLRARRLLTPRRTRRLLSLVWVASLGLALPMAVIMGQKHEVESADGEPEPASRVCTVLVSRATLQVFIQVNVLVSFALPLALTAFLNGITVNHLMALYSQVPSASAQVSSIPSRLELLSEEGLLGFITWRKTLSLGVQASLVRHKDASQIRSLQHSAQVLRAIVAVYVICWLPYHARRLMYCYIPDDGWTNELYDFYHYFYMVTNTLFYVSSAVTPILYNAVSSSFRKLFLESLGSLCGEQHSLVPLPQEAPESTTSTYSFRLWGSPRNPSLGEIQV
UniProt	Q63384
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5106
IUPHAR	310
DrugBank	N/A

Ligand

Name	CHEMBL3290089
Molecular formula	C31H31ClN4O3
IUPAC name	N-(2-adamantyl)-1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
Molecular weight	543.064
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.4
Synonyms	BDBM50019426 SCHEMBL17114634
Inchi Key	LWSJPDMZBABZMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H31ClN4O3/c1-38-27-4-3-5-28(39-2)29(27)26-16-24(31(37)34-30-19-11-17-10-18(13-19)14-20(30)12-17)35-36(26)25-8-9-33-23-15-21(32)6-7-22(23)25/h3-9,15-20,30H,10-14H2,1-2H3,(H,34,37)
PubChem CID	90644400
ChEMBL	CHEMBL3290089
IUPHAR	N/A
BindingDB	50019426
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	62.0 nM	PMID24856674	BindingDB,ChEMBL

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