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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701951
Molecular formula	C19H18ClN3O
IUPAC name	8-chloro-N-[4-[(2S)-morpholin-2-yl]phenyl]quinolin-2-amine
Molecular weight	339.823
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.7
Synonyms	BDBM129410 SCHEMBL12610002 US8802673, 52
Inchi Key	LQLYWBRGYCYYGN-QGZVFWFLSA-N
Inchi ID	InChI=1S/C19H18ClN3O/c20-16-3-1-2-14-6-9-18(23-19(14)16)22-15-7-4-13(5-8-15)17-12-21-10-11-24-17/h1-9,17,21H,10-12H2,(H,22,23)/t17-/m1/s1
PubChem CID	60200772
ChEMBL	CHEMBL3701951
IUPHAR	N/A
BindingDB	129410
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	0.5 nM	, None	BindingDB,ChEMBL

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