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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701915
Molecular formula	C15H15N5O
IUPAC name	2-[4-[(2S)-morpholin-2-yl]anilino]pyrimidine-5-carbonitrile
Molecular weight	281.319
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	0.8
Synonyms	BDBM129374 SCHEMBL12609898 US8802673, 16
Inchi Key	LQKRWYFWHIWOMV-CQSZACIVSA-N
Inchi ID	InChI=1S/C15H15N5O/c16-7-11-8-18-15(19-9-11)20-13-3-1-12(2-4-13)14-10-17-5-6-21-14/h1-4,8-9,14,17H,5-6,10H2,(H,18,19,20)/t14-/m1/s1
PubChem CID	68325637
ChEMBL	CHEMBL3701915
IUPHAR	N/A
BindingDB	129374
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	27.6 nM	, None	BindingDB,ChEMBL

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