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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701970
Molecular formula	C17H20ClN3O2
IUPAC name	6-chloro-5-ethoxy-N-[4-[(2S)-morpholin-2-yl]phenyl]pyridin-3-amine
Molecular weight	333.816
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.7
Synonyms	BDBM129429 SCHEMBL12610108 US8802673, 71
Inchi Key	LMSQUCVEFRGNAE-MRXNPFEDSA-N
Inchi ID	InChI=1S/C17H20ClN3O2/c1-2-22-15-9-14(10-20-17(15)18)21-13-5-3-12(4-6-13)16-11-19-7-8-23-16/h3-6,9-10,16,19,21H,2,7-8,11H2,1H3/t16-/m1/s1
PubChem CID	86766840
ChEMBL	CHEMBL3701970
IUPHAR	N/A
BindingDB	129429
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	11.8 nM	, None	BindingDB,ChEMBL

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