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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H1 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH1
Synonym	H1R HH1R
Disease	N/A for non-human GPCRs
Length	488
Amino acid sequence	MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFPITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGCIMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTFKRILRIPP
UniProt	P31389
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3943
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	AC1LQZR1
Molecular formula	C27H30N4O
IUPAC name	1-[3-(4-benzhydrylpiperazin-1-ium-1-yl)propyl]benzimidazol-2-olate
Molecular weight	426.564
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.4
Synonyms	1-[3-(4-benzhydrylpiperazin-1-ium-1-yl)propyl]benzimidazol-2-olate STL046521 MCULE-7893533906 1-{3-[4-(diphenylmethyl)piperazin-1-ium-1-yl]propyl}-1H-benzimidazol-2-olate AKOS005699997 MolPort-000-714-823 [ Show all ]
Inchi Key	BAINIUMDFURPJM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32)
PubChem CID	1385580
ChEMBL	CHEMBL13828
IUPHAR	N/A
BindingDB	76863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
A10	0.014 mg l-1	PMID4068010	ChEMBL
IC50	9.0 nM	PMID2562852	BindingDB,ChEMBL

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