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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701964
Molecular formula	C17H18N2O3
IUPAC name	N-[4-[(2S)-morpholin-2-yl]phenyl]-1,3-benzodioxol-5-amine
Molecular weight	298.342
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.3
Synonyms	SCHEMBL12609845 US8802673, 65 BDBM129423
Inchi Key	LFWYZARXTBIWQA-QGZVFWFLSA-N
Inchi ID	InChI=1S/C17H18N2O3/c1-3-13(4-2-12(1)17-10-18-7-8-20-17)19-14-5-6-15-16(9-14)22-11-21-15/h1-6,9,17-19H,7-8,10-11H2/t17-/m1/s1
PubChem CID	68325602
ChEMBL	CHEMBL3701964
IUPHAR	N/A
BindingDB	129423
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	13.1 nM	, None	BindingDB,ChEMBL

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