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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 35
Species	Homo sapiens (Human)
Gene	GPR35
Synonym	G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor
Disease	N/A
Length	309
Amino acid sequence	MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
UniProt	Q9HC97
Protein Data Bank	N/A
GPCR-HGmod model	Q9HC97
3D structure model	This predicted structure model is from GPCR-EXP Q9HC97.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293267
IUPHAR	102
DrugBank	BE0005562

Ligand

Name	CHEMBL2392147
Molecular formula	C14H11NO7
IUPAC name	8-[(3-methoxy-3-oxopropanoyl)amino]-4-oxochromene-2-carboxylic acid
Molecular weight	305.242
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.0
Synonyms	BDBM50436027
Inchi Key	LAYJYCGUQOCKGQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H11NO7/c1-21-12(18)6-11(17)15-8-4-2-3-7-9(16)5-10(14(19)20)22-13(7)8/h2-5H,6H2,1H3,(H,15,17)(H,19,20)
PubChem CID	71734943
ChEMBL	CHEMBL2392147
IUPHAR	N/A
BindingDB	50436027
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	20200.0 nM	PMID23713606	BindingDB,ChEMBL
Emax	87.0 %	PMID23713606	ChEMBL
Ki	18600.0 nM	PMID23888932	BindingDB,ChEMBL

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