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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Canis lupus familiaris (Dog)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	415
Amino acid sequence	MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
UniProt	P54833
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2289
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL40679
Molecular formula	C17H24N2O2
IUPAC name	1-(dicyclopropylmethylideneamino)oxy-3-(2-methylanilino)propan-2-ol
Molecular weight	288.391
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.9
Synonyms	Dicyclopropyl-methanone O-(2-hydroxy-3-o-tolylamino-propyl)-oxime BDBM50064208 Dicyclopropyl ketone O-[2-hydroxy-3-[(2-methylphenyl)amino]propyl]oxime
Inchi Key	AZJJSKOUHVSHNT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H24N2O2/c1-12-4-2-3-5-16(12)18-10-15(20)11-21-19-17(13-6-7-13)14-8-9-14/h2-5,13-15,18,20H,6-11H2,1H3
PubChem CID	10643362
ChEMBL	CHEMBL40679
IUPHAR	N/A
BindingDB	50064208
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<10000.0 nM	PMID9572886	BindingDB,ChEMBL

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