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Name | G-protein coupled receptor 35 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Gpr35 |
Synonym | G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor |
Disease | N/A for non-human GPCRs |
Length | 307 |
Amino acid sequence | MNSTTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMHQWTETRIYMTNLAVADLCLLCSLPFVLYSLKYSSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGGFCFSSQTRRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLNTCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATSSNTPHKSQDSQILSLT |
UniProt | Q9ES90 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2390813 |
IUPHAR | 102 |
DrugBank | N/A |
Name | CHEMBL2392156 |
---|---|
Molecular formula | C18H10F3NO5 |
IUPAC name | 4-oxo-8-[[4-(trifluoromethyl)benzoyl]amino]chromene-2-carboxylic acid |
Molecular weight | 377.275 |
Hydrogen bond acceptor | 8 |
Hydrogen bond donor | 2 |
XlogP | 3.0 |
Synonyms | BDBM50436030 |
Inchi Key | KWQQLPCMVMIVLX-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C18H10F3NO5/c19-18(20,21)10-6-4-9(5-7-10)16(24)22-12-3-1-2-11-13(23)8-14(17(25)26)27-15(11)12/h1-8H,(H,22,24)(H,25,26) |
PubChem CID | 71735035 |
ChEMBL | CHEMBL2392156 |
IUPHAR | N/A |
BindingDB | 50436030 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 23.0 % | PMID23713606 | ChEMBL |
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