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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Canis lupus familiaris (Dog)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	415
Amino acid sequence	MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
UniProt	P54833
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2289
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL349978
Molecular formula	C20H26N4O4S
IUPAC name	4-(methanesulfonamido)-N-[[4-(2-methoxyphenyl)piperazin-2-yl]methyl]benzamide
Molecular weight	418.512
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	1.4
Synonyms	BDBM50001906 N-[4-(2-Methoxyphenyl)-2-piperazinylmethyl]-4-(methylsulfonylamino)benzamide 4-Methanesulfonylamino-N-[4-(2-methoxy-phenyl)-piperazin-2-ylmethyl]-benzamide SCHEMBL9668252
Inchi Key	KSSFMKSIGXBNOC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H26N4O4S/c1-28-19-6-4-3-5-18(19)24-12-11-21-17(14-24)13-22-20(25)15-7-9-16(10-8-15)23-29(2,26)27/h3-10,17,21,23H,11-14H2,1-2H3,(H,22,25)
PubChem CID	14998850
ChEMBL	CHEMBL349978
IUPHAR	N/A
BindingDB	50001906
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	630.0 nM	PMID1347318	BindingDB,ChEMBL

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