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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Canis lupus familiaris (Dog)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	415
Amino acid sequence	MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
UniProt	P54833
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2289
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	51639-48-6
Molecular formula	C12H16N2O
IUPAC name	1-(4-piperazin-1-ylphenyl)ethanone
Molecular weight	204.273
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	0.9
Synonyms	AX8014119 CHEMBL166330 FT-0617368 MFCD00005962 Piperazin-4-ylacetophenone ST24037298 1-(4-Piperazin-1-yl-phenyl)-ethanone ZX-AT004644 1-[4-(piperazin-1-yl)phenyl]ethan-1-one 4-piperazino acetophenone AC1Q1JPC BDBM50001899 DTXSID00199584 KB-147069 NSC-109890 SC-62400 1-(4-(piperazin-1-yl)phenyl)ethanone TR-018393 1-(4-piperazine-1-yl-phenyl)-ethanone 4'-(Piperazin-1-yl)acetophenone ACM51639486 CC-02154 Ethanone,1-[4-(1-piperazinyl)phenyl]- KS-00002BJA p-Piperazinoacetophenone SR-01000059922-1 1-(4-acetylphenyl)-piperazine X-4409 1-[4-(1-Piperazinyl)phenyl]-1-ethanone 4'-Piperazinoacetophenone, 94% AB0118188 AK122324 BBL016329 CTK4J4599 I13-0287 MolPort-000-006-194 PubChem13361 STK400476 1-(4-Piperazin-1-yl-phenyl)ethanone 1-[4-(piperazin-1-yl)phenyl]ethanone 4-piperazinoacetophenone AC1Q1JPD BIDD:GT0584 EINECS 257-332-6 KB-147467 NSC109890 SCHEMBL232986 1-(4-Acetyl-phenyl)piperazine TS-02904 1-(p-acetylphenyl)piperazine 4'-piperazino-acetophenone ACMC-1AM8S F2190-0511 MCULE-2994216639 P67186 ST042067 1-(4-acetylphenyl)piperazine ZINC29076 1-[4-(1-Piperazinyl)phenyl]ethanone # 4-(4-acetylphenyl)piperazine AC1L3Y5U AKOS000120540 BB_SC-01973 DB-018540 InChI=1/C12H16N2O/c1-10(15)11-2-4-12(5-3-11)14-8-6-13-7-9-14/h2-5,13H,6-9H2,1H n-(4-acetylphenyl)piperazine SBB055067 1-(4-(piperazin-1-yl)phenyl)ethan-1-one STR06370 1-(4-piperazin-1-ylphenyl)ethanone 4'-(1-Piperazino)acetophenone C12H16N2O 204.27 93-98 degrees 51639-48-6 257-332-6 MFCD00005962 UN3259 8 N 4-Piperazinoacetophenone, 94% AC1Q5DY9 C-10008 Ethanone, 1-[4-(1-piperazinyl)phenyl]- KPXVKKBJROCIJB-UHFFFAOYSA-N OR0219 SR-01000059922 1-(4-acetylphenyl) piperazine VP70144 1-acetyl-4-piperazinylbenzene 4'-Piperazinoacetophenone 7213AB AJ-08480 [ Show all ]
Inchi Key	KPXVKKBJROCIJB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H16N2O/c1-10(15)11-2-4-12(5-3-11)14-8-6-13-7-9-14/h2-5,13H,6-9H2,1H3
PubChem CID	97269
ChEMBL	CHEMBL166330
IUPHAR	N/A
BindingDB	50001899
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<100000.0 nM	PMID1347318	BindingDB,ChEMBL

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