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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Canis lupus familiaris (Dog)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	415
Amino acid sequence	MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
UniProt	P54833
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2289
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL290024
Molecular formula	C22H26N2O2
IUPAC name	1-(dicyclopropylmethylideneamino)oxy-3-(2-phenylanilino)propan-2-ol
Molecular weight	350.462
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.1
Synonyms	Dicyclopropyl ketone O-[2-hydroxy-3-[(1,1'-biphenyl-2-yl)amino]propyl]oxime Dicyclopropyl-methanone O-[3-(biphenyl-2-ylamino)-2-hydroxy-propyl]-oxime BDBM50064230
Inchi Key	KNCNOSADGGQHIX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N2O2/c25-19(15-26-24-22(17-10-11-17)18-12-13-18)14-23-21-9-5-4-8-20(21)16-6-2-1-3-7-16/h1-9,17-19,23,25H,10-15H2
PubChem CID	10596336
ChEMBL	CHEMBL290024
IUPHAR	N/A
BindingDB	50064230
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<10000.0 nM	PMID9572886	BindingDB,ChEMBL

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