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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 2
Species	Mus musculus (Mouse)
Gene	P2ry2
Synonym	Purinergic receptor P2Y2 receptor P2Y2 P2Y purinoceptor 2 ATP receptor P2Y ATP receptor 2 P2U1 P2U purinoceptor 1 purinergic receptor P2Y [ Show all ]
Disease	N/A for non-human GPCRs
Length	373
Amino acid sequence	MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
UniProt	P35383
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075298
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL584184
Molecular formula	C9H17N2O11P3
IUPAC name	5-(2,4-dioxopyrimidin-1-yl)pentyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid
Molecular weight	422.159
Hydrogen bond acceptor	11
Hydrogen bond donor	5
XlogP	-3.7
Synonyms	BDBM50378133 SCHEMBL624295
Inchi Key	KIDOXWQUUCRMFM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H17N2O11P3/c12-8-4-6-11(9(13)10-8)5-2-1-3-7-23(14,15)21-25(19,20)22-24(16,17)18/h4,6H,1-3,5,7H2,(H,14,15)(H,19,20)(H,10,12,13)(H2,16,17,18)
PubChem CID	45481635
ChEMBL	CHEMBL584184
IUPHAR	N/A
BindingDB	50378133
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
IC50	166000.0 nM	PMID19523835	BindingDB,ChEMBL

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