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Name | Melatonin receptor type 1C |
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Species | Gallus gallus (Chicken) |
Gene | |
Synonym | CKB Mel-1C-R Mel1c receptor |
Disease | N/A for non-human GPCRs |
Length | 346 |
Amino acid sequence | MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL |
UniProt | P49288 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3196 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL285477 |
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Molecular formula | C14H18N2O3 |
IUPAC name | N-[2-(5,7-dimethoxy-1H-indol-3-yl)ethyl]acetamide |
Molecular weight | 262.309 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 2 |
XlogP | 1.6 |
Synonyms | N-[2-(5,7-Dimethoxy-1H-indole-3-yl)ethyl]acetamide |
Inchi Key | KANOAYGDYDNMMG-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C14H18N2O3/c1-9(17)15-5-4-10-8-16-14-12(10)6-11(18-2)7-13(14)19-3/h6-8,16H,4-5H2,1-3H3,(H,15,17) |
PubChem CID | 10611502 |
ChEMBL | CHEMBL285477 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Relative affinity | 211.0 - | PMID9748358 | ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417