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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	D(1A) dopamine receptor
Species	Mus musculus (Mouse)
Gene	Drd1
Synonym	D1 receptor D1A DADR Dopamine D1 receptor Dopamine-1A receptor Gpcr15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MAPNTSTMDETGLPVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDAEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKREEAGGIPKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
UniProt	Q61616
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3071
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	NAPTALAM
Molecular formula	C18H13NO3
IUPAC name	2-(naphthalen-1-ylcarbamoyl)benzoic acid
Molecular weight	291.306
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM81777 Peach Thin 322 CAS-132-66-1 SBB008186 DSSTox_GSID_32437 UNII-306R88V86P Grelutin .alpha.-Naphthylphthalamic acid JXTHEWSKYLZVJC-UHFFFAOYSA-N 2-((1-Naphthalenylamino)carbonyl)benzoic acid MolPort-000-389-108 2-[(1-Naphthylamino)carbonyl]benzoic acid # N-.alpha.-Naphthylphthalamic acid ACP 322 N-alpha-Naphthylphthalamic acid Alanap 1 Naptalam [BSI:ISO] alanap10gat NPA (VAN) NSC-204421 Benzoic acid, 2-[(1-naphthalenylamino)carbonyl]- Phthalamic acid, N-1-naphthyl- CHEBI:60833 SR-01000392378 Dyanap I14-18114 1-Naphthylphthalamic acid Kyselina N-1-naftylftalamova 2-(1-Naphthylcarbamoyl)benzoic acid N-(.alpha.-Naphthyl)phthalamic acid 306R88V86P N-1-Naphthyl-phthalamidsaeure [German] AI3-23463 Naftalam Alanap 3 Naptalame Analape ARONIS018728 Oprea1_065903 BRN 2814102 Premerge plus (Salt/Mix) Cyanap STK072761 FR-1032 J-006203 132-67-2 (hydrochloride salt) LS-109086 2-[(1-Naphthalenylamino)carbonylbenzoic acid N-(1-Naphthyl)phthalamicAcid AC1L1RBG N-1-Naphthylphthalamidic acid AKOS000485934 Naphthylphthalamic acid alanap1 NCGC00255281-01 Benzoic acid, 2-((1-naphthalenylamino)carbonyl)- Peach-Thin Caswell No. 592 SCHEMBL54940 DSSTox_RID_78947 WLN: L66J BMVR BVQ HMS1414N13 1-(N-Naphthyl)Phthalamic acid KS-000013CA 2-((1-naphthalenylamino)carbonyl)benzoicacid Mor-Cran 2-[N-(1-naphthylcarbamoyl)]benzoic acid N-1-Naphthalenephthalamic acid acp322 N-Naphthalen-1-yl-phthalamic acid Alanap 10G Naptalam, analytical standard Alanape NPA,(-) NSC204421 Benzoic acid, 2-[(1-naphthalenylamino)carbonyl]- (9CI) Phthalamic acid, N-1-naphthyl- (7CI,8CI) CHEMBL2447888 SR-01000392378-1 EPA Pesticide Chemical Code 030702 IFLab1_001003 112284-33-0 Kyselina N-1-naftylftalamova [Czech] 2-(N-naphthylcarbamoyl)benzoic acid N-(1-naphthalenyl)phthalamic acid 6Q8 N-1-Naphthylphthalamate AJ-08466 Naftalam [Czech] Alanap Plus Naptalame [ISO-French] Ancrack ZINC28113 BB0274029 Oprea1_469302 C18869 RTR-004458 DSSTox_CID_12437 Tox21_302279 FT-0629075 JXTHEWSKYLZVJC-UHFFFAOYSA- 2-((1-naphthalenylamino)carbonyl)-benzoicaci MCULE-3496128683 2-[(1-Naphthylamino)carbonyl]benzoic acid N-(1-Naphthyl)phthalamidic acid ACMC-209bpp N-1-napthylphthalamic acid Alanap alanap10g Nip-a-thin NSC 204421 Benzoic acid, 2-((1-naphthalenylamino)carbonyl)- (9CI) Phthalamic acid, N-1-naphthyl CBDivE_002040 Solo (Salt/Mix) DTXSID6032437 HSDB 1742 1-N-Naphthylphthalamic acid KS-00004AUE 2-((1-Naphthalenylamino)carbonylbenzoic acid N - (1 - Naphthyl)phthalamic acid 3-12-00-02876 (Beilstein Handbook Reference) N-1-Naphthyl-phthalamidsaeure AE-017/30049056 N0067 Alanap 10G at Naptalam, PESTANAL(R), analytical standard alpha-Naphthylphthalamic acid NSC_8594 Benzoic acid, 2-[(naphthalenylamino)carbonyl]- Phthalamic acid,N-1-naphthyl- CTK0D2202 ST001288 F0290-1094 InChI=1/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) 132-66-1 L001060 2-(naphthalen-1-ylcarbamoyl)benzoic acid N-(1-Naphthyl)phthalamic acid N-1-Naphthylphthalamic acid AK-57895 Naphthalam Alanap-2 Naptro ANW-19451 [3H]-NPA [ Show all ]
Inchi Key	JXTHEWSKYLZVJC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22)
PubChem CID	8594
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81777
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	480.0 nM	PMID2895008	BindingDB

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