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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Cavia porcellus (Guinea pig)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
UniProt	P47745
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2304404
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	1-methyl-3-ethylxanthine
Molecular formula	C8H10N4O2
IUPAC name	3-ethyl-1-methyl-7H-purine-2,6-dione
Molecular weight	194.194
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	0.5
Synonyms	125573-05-9 CHEMBL334813 3-Ethyl-1-methyl-3,7-dihydro-purine-2,6-dione BDBM50001510 1H-Purine-2,6-dione, 3-ethyl-3,7-dihydro-1-methyl- CTK0F6869 3-Ethyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione DTXSID30579759 ACMC-1C0N4 [ Show all ]
Inchi Key	JUZUUEGSTBASHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C8H10N4O2/c1-3-12-6-5(9-4-10-6)7(13)11(2)8(12)14/h4H,3H2,1-2H3,(H,9,10)
PubChem CID	15931309
ChEMBL	CHEMBL334813
IUPHAR	N/A
BindingDB	50001510
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC15	28.5 uM	PMID1331453	ChEMBL
Ki	7600.0 nM	PMID1331453	BindingDB,ChEMBL

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