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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	P20288
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3998
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	UNII-YZC2Y51NHJ
Molecular formula	C16H17NO2
IUPAC name	(5R)-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Molecular weight	255.317
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.5
Synonyms	62751-59-1 SK-383933 (R)-1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (R)-SKF-38393 AJ-32307 CTK2B3174 UNII-R7TF327S2C component JUDKOGFHZYMDMF-CQSZACIVSA-N (+)-SKF-38393 CHEBI:125624 SCHEMBL7941051 ZINC1996374 (1R)-2,3,4,5-Tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol (R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393) CHEMBL24077 SKF 38393 (+) 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393) BDBM50004822 R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (1R)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol CHEBI:131800 SK&F-383933 (5R)-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol (R)-SKF 38393 AC1OAA0J CHEMBL503958 SKF-38393, (R)- 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, (1R)- BDBM50274530 R-(+)-Skf 38393 YZC2Y51NHJ (1R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hyrobromide [ Show all ]
Inchi Key	JUDKOGFHZYMDMF-CQSZACIVSA-N
Inchi ID	InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1
PubChem CID	6852376
ChEMBL	CHEMBL24077
IUPHAR	N/A
BindingDB	50004822, 50274530
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
K bind	33.9 uM	PMID2886663	ChEMBL

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