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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL632058
Molecular formula	C16H17N3
IUPAC name	N-ethyl-N-(1H-imidazol-5-ylmethyl)naphthalen-2-amine
Molecular weight	251.333
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.3
Synonyms	US8586617, 82 CHEMBL3645397 BDBM106603
Inchi Key	AWAKTMGMXAQNLJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17N3/c1-2-19(11-15-10-17-12-18-15)16-8-7-13-5-3-4-6-14(13)9-16/h3-10,12H,2,11H2,1H3,(H,17,18)
PubChem CID	24947335
ChEMBL	CHEMBL3645397
IUPHAR	N/A
BindingDB	106603
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.2 nM	, None	BindingDB,ChEMBL

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