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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M1
Species	Rattus norvegicus (Rat)
Gene	Chrm1
Synonym	cholinergic receptor, muscarinic 1 cholinergic receptor, muscarinic 1, CNS cholinergic receptor M1 muscarinic acetylcholine receptor M1 receptor M1R Chrm-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	460
Amino acid sequence	MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
UniProt	P08482
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL276
IUPHAR	13
DrugBank	N/A

Ligand

Name	hydroxylamine
Molecular formula	H3NO
IUPAC name	hydroxylamine
Molecular weight	33.03
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	-1.2
Synonyms	amino-alcohol CCG-204724 DTXSID7041043 HONH2 Hydroxylamin Hydroxylazane LS-96747 NCGC00015527-03 oxidoazanium AC1L1A0W AC1Q556X Azanol CHEMBL1191361 Epitope ID:117722 HYDROXYAMINE Hydroxylamine hydrochloride in combination with isoniazid and rifampicin J-502073 MolPort-001-779-718 Nitrinous acid (1) hydroxylamine UNII-2FP81O2L9Z amine N-oxide BDBM50082140 DB-080981 H2NHO hydroxyl amine Hydroxylamine solution, 50 wt. % in H2O, 99.999% Lopac0_000637 NCGC00015527-01 Nitroxide 2FP81O2L9Z AC1L4OJJ arninoalcohol CHEBI:15429 EC 232-259-2 HSDB 579 hyroxylamine MCULE-3913133443 NCGC00162208-01 Oxyammonia AC1Q7DDD azinous acid CTK2H8929 FT-0627150 HYDROXYAMINO GROUP Hydroxylamine solution KS-00000V4I MRF-0000034 Nitrogen oxide (NOx) (hydroxyamino)methanol [NH2OH] amino alcohol C00192 dihydridohydroxidonitrogen H2NOH hydroxyl-amine Hydroxylaminesolution LS-77353 NCGC00015527-02 Oxammonium 7803-49-8 AC1Q2260 AVXURJPOCDRRFD-UHFFFAOYSA-N EINECS 232-259-2 hydroxy amine Hydroxylamine (50% solution in water) I05-2702 MFCD00044522 NH2OH SC-51896 AKOS009031565 BCP03655 CTK8G5726 H2N-OH Hydroxyazane Hydroxylamine solution, 50 wt. % in H2O Lopac-H-9876 N-hydroxyamine Nitrogen oxides 2FFDCFE4-66E9-4869-8F4D-DC8E410797E7 [ Show all ]
Inchi Key	AVXURJPOCDRRFD-UHFFFAOYSA-N
Inchi ID	InChI=1S/H3NO/c1-2/h2H,1H2
PubChem CID	787
ChEMBL	CHEMBL1191361
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Potency	28.2 nM	PubChem BioAssay data set	ChEMBL

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