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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thyrotropin-releasing hormone receptor
Species	Mus musculus (Mouse)
Gene	Trhr
Synonym	Thyroliberin receptor TRH receptor TRH-R TRH-R1 TRH1 receptor
Disease	N/A for non-human GPCRs
Length	393
Amino acid sequence	MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELEDITVTDTYVSTTKVSFDDTCLASEN
UniProt	P21761
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2467
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL180789
Molecular formula	C20H18ClN3O3
IUPAC name	N-butan-2-yl-1-(2-chloro-5-nitrophenyl)isoquinoline-3-carboxamide
Molecular weight	383.832
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.2
Synonyms	N/A
Inchi Key	JOEJSBQZAAFMQL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18ClN3O3/c1-3-12(2)22-20(25)18-10-13-6-4-5-7-15(13)19(23-18)16-11-14(24(26)27)8-9-17(16)21/h4-12H,3H2,1-2H3,(H,22,25)
PubChem CID	44390503
ChEMBL	CHEMBL180789
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Competition	33.0 %	PMID15664847	ChEMBL
Competition	65.0 %	PMID15664847	ChEMBL

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