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Name | G-protein coupled receptor 35 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Gpr35 |
Synonym | G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor |
Disease | N/A for non-human GPCRs |
Length | 307 |
Amino acid sequence | MNSTTCNSTLTWPASVNNFFIIYSALLLVLGLLLNSVALWVFCYRMHQWTETRIYMTNLAVADLCLLCSLPFVLYSLKYSSSDTPVCQLSQGIYLANRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAAAVCVALWVIVVTSLVVRWRLGMQEGGFCFSSQTRRNFSTTAFSLLGFYLPLAIVVFCSLQVVTVLSRRPAADVGQAEATQKATHMVWANLAVFVICFLPLHVVLTVQVSLNLNTCAARDTFSRALSITGKLSDTNCCLDAICYYYMAREFQEASKPATSSNTPHKSQDSQILSLT |
UniProt | Q9ES90 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2390813 |
IUPHAR | 102 |
DrugBank | N/A |
Name | CHEMBL2392142 |
---|---|
Molecular formula | C10H5NO6 |
IUPAC name | 8-nitro-4-oxochromene-2-carboxylic acid |
Molecular weight | 235.151 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | 1.5 |
Synonyms | SCHEMBL4250005 8-Nitro-4-oxo-4H-1-benzopyran-2-carboxylic acid BDBM50436038 JNMUUGPMODDSNA-UHFFFAOYSA-N 8-nitro-2-carboxy-4-oxo-4H-1-benzopyran |
Inchi Key | JNMUUGPMODDSNA-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C10H5NO6/c12-7-4-8(10(13)14)17-9-5(7)2-1-3-6(9)11(15)16/h1-4H,(H,13,14) |
PubChem CID | 21982642 |
ChEMBL | CHEMBL2392142 |
IUPHAR | N/A |
BindingDB | 50436038 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 4.0 % | PMID23713606 | ChEMBL |
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