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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL631995
Molecular formula	C15H18ClN3
IUPAC name	3-chloro-N-(1-cyclopropylethyl)-N-(1H-imidazol-5-ylmethyl)aniline
Molecular weight	275.78
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.5
Synonyms	US8586617, 52 CHEMBL3645386 BDBM106591
Inchi Key	AVOHLFDGFOUCRQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H18ClN3/c1-11(12-5-6-12)19(9-14-8-17-10-18-14)15-4-2-3-13(16)7-15/h2-4,7-8,10-12H,5-6,9H2,1H3,(H,17,18)
PubChem CID	59728044
ChEMBL	CHEMBL3645386
IUPHAR	N/A
BindingDB	106591
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	4.0 nM	, None	BindingDB,ChEMBL

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