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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-X-C chemokine receptor type 3
Species	Rattus norvegicus (Rat)
Gene	Cxcr3
Synonym	IP-10 receptor Interferon-inducible protein 10 receptor GPR9 G protein-coupled receptor 9 Cxcr3 CXCR-3 CXC-R3 CKR-L2 chemokine (C-X-C motif) receptor 3 CD183 MigR [ Show all ]
Disease	N/A for non-human GPCRs
Length	367
Amino acid sequence	MYLEVSERQVLDASDIAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPVLYSLLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAAQWVFGSGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPWVRVALTCIVVWGLCVLFALPDFIFLSASHDQRLNATHCQYNFPQVGRTALRVLQLVAGFLMPLLVMAYCYAHILAVLLVSRGQRRFRAMRLVVVVVVAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFVGVKFKEQMWMLLMRLGRSDQRGPQRQPSSSRRESSWSETTEASYLGL
UniProt	Q9JII9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075172
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1809038
Molecular formula	C28H30N4O3
IUPAC name	(6aR,9R)-4-(2-hydroxyethyl)-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Molecular weight	470.573
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.0
Synonyms	BDBM50349672 SCHEMBL3186733
Inchi Key	JLYWDONWNIMGQM-CJFMBICVSA-N
Inchi ID	InChI=1S/C28H30N4O3/c33-14-13-31-17-19-16-25-23(22-9-6-10-24(31)26(19)22)15-20(27(34)30-11-4-5-12-30)18-32(25)28(35)29-21-7-2-1-3-8-21/h1-3,6-10,15,17,20,25,33H,4-5,11-14,16,18H2,(H,29,35)/t20-,25-/m1/s1
PubChem CID	56680574
ChEMBL	CHEMBL1809038
IUPHAR	N/A
BindingDB	50349672
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	7.0 nM	PMID21764306	BindingDB,ChEMBL

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