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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Bombesin receptor subtype-3
Species	Homo sapiens (Human)
Gene	BRS3
Synonym	bombesin receptor subtype-3 BRS-3 bombesin like receptor 3 BB3 receptor bb3
Disease	Breast cancer Cancer
Length	399
Amino acid sequence	MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
UniProt	P32247
Protein Data Bank	N/A
GPCR-HGmod model	P32247
3D structure model	This predicted structure model is from GPCR-EXP P32247.
BioLiP	N/A
Therapeutic Target Database	T68887
ChEMBL	CHEMBL4080
IUPHAR	40
DrugBank	N/A

Ligand

Name	CHEMBL1099034
Molecular formula	C24H26N6
IUPAC name	5-[2-[4-[2-[5-(cyclopentylmethyl)-1H-imidazol-2-yl]ethyl]phenyl]phenyl]-2H-tetrazole
Molecular weight	398.514
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.6
Synonyms	BDBM50316909 5-(4''-(2-(4-(cyclopentylmethyl)-2H-imidazol-2-yl)ethyl)biphenyl-2-yl)-1H-tetrazole
Inchi Key	AVFLPCCKTSYVRA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N6/c1-2-6-18(5-1)15-20-16-25-23(26-20)14-11-17-9-12-19(13-10-17)21-7-3-4-8-22(21)24-27-29-30-28-24/h3-4,7-10,12-13,16,18H,1-2,5-6,11,14-15H2,(H,25,26)(H,27,28,29,30)
PubChem CID	46889145
ChEMBL	CHEMBL1099034
IUPHAR	N/A
BindingDB	50316909
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	112.0 %	PMID20347296	ChEMBL
EC50	56.0 nM	PMID20347296	BindingDB,ChEMBL
IC50	15.0 nM	PMID20347296	BindingDB,ChEMBL

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