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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701936
Molecular formula	C16H18FN3O
IUPAC name	N-[(5-fluoropyridin-2-yl)methyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	287.338
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.5
Synonyms	US8802673, 37 BDBM129395 SCHEMBL12609843
Inchi Key	JJBBQXYNZOTPMZ-MRXNPFEDSA-N
Inchi ID	InChI=1S/C16H18FN3O/c17-13-3-6-15(19-9-13)10-20-14-4-1-12(2-5-14)16-11-18-7-8-21-16/h1-6,9,16,18,20H,7-8,10-11H2/t16-/m1/s1
PubChem CID	68325601
ChEMBL	CHEMBL3701936
IUPHAR	N/A
BindingDB	129395
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	129.2 nM	, None	BindingDB,ChEMBL

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