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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Canis lupus familiaris (Dog)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	415
Amino acid sequence	MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
UniProt	P54833
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2289
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	1-(3-Methylphenyl)piperazine
Molecular formula	C11H16N2
IUPAC name	1-(3-methylphenyl)piperazine
Molecular weight	176.263
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.8
Synonyms	3-methyl phenylpiperazine AC1L34Q8 BDBM50001904 EN300-23498 JIWHIRLNKIUYSM-UHFFFAOYSA- NSC-184825 ST50405818 1-(m-Methylphenyl)piperazine 4-m-tolyl-piperazine ACMC-1AK0R CHEMBL165175 FT-0605635 KS-000011UM Piperazine,1-(3-methylphenyl)- VP70140 1-m-tolyl-piperzine ALBB-005958 DTXSID30194108 InChI=1/C11H16N2/c1-10-3-2-4-11(9-10)13-7-5-12-6-8-13/h2-4,9,12H,5-8H2,1H3 MolPort-000-157-424 SBB027338 1-(3-methylphenyl) piperazine 3-methylphenylpiperazine AC1Q2H5V BP-10761 F2190-0518 JIWHIRLNKIUYSM-UHFFFAOYSA-N NSC184825 STK500994 1-(3-Methylphenyl)piperazine, 99% 1-(m-Tolyl)piperazine 4-m-tolylpiperazine AJ-10179 CTK4I4375 I13-446 Maybridge4_000089 R1690 ZINC66066 (3-methylphenyl)piperazine 1-m-tolylpiperazine 5647AB ANW-29582 EINECS 255-251-0 J-503165 NCIOpen2_003566 SCHEMBL81365 1-(3-Methylphenyl)-piperazine 4-(3-methylphenyl)piperazine AC1Q2H5W FS-1235 KB-12968 Piperazine, 1-(3-methylphenyl)- TR-016365 1-(3-Methylphenyl)piperazine, >=97.5% (HPLC) 1-m-Tolyl-piperazine 41186-03-2 AKOS000101165 DB-024582 IDI1_030671 MCULE-1229085646 RL03590 1-(3-methyl phenyl)piperazine [ Show all ]
Inchi Key	JIWHIRLNKIUYSM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H16N2/c1-10-3-2-4-11(9-10)13-7-5-12-6-8-13/h2-4,9,12H,5-8H2,1H3
PubChem CID	83111
ChEMBL	CHEMBL165175
IUPHAR	N/A
BindingDB	50001904
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	40000.0 nM	PMID1347318	BindingDB,ChEMBL

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