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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL632523
Molecular formula	C19H20FN3O
IUPAC name	4-fluoro-N-(1H-imidazol-5-ylmethyl)-3-phenoxy-N-propan-2-ylaniline
Molecular weight	325.387
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.1
Synonyms	US8586617, 208 CHEMBL3645432 BDBM106640
Inchi Key	AVBWUVOOKROSBS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20FN3O/c1-14(2)23(12-15-11-21-13-22-15)16-8-9-18(20)19(10-16)24-17-6-4-3-5-7-17/h3-11,13-14H,12H2,1-2H3,(H,21,22)
PubChem CID	24948080
ChEMBL	CHEMBL3645432
IUPHAR	N/A
BindingDB	106640
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3.0 nM	, None	BindingDB,ChEMBL

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