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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3701969
Molecular formula	C18H21ClN2O
IUPAC name	N-[1-(4-chlorophenyl)ethyl]-4-[(2S)-morpholin-2-yl]aniline
Molecular weight	316.829
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.6
Synonyms	BDBM129428 SCHEMBL12609817 US8802673, 70
Inchi Key	JFIRPSVVFUGHGX-PQJIZZRHSA-N
Inchi ID	InChI=1S/C18H21ClN2O/c1-13(14-2-6-16(19)7-3-14)21-17-8-4-15(5-9-17)18-12-20-10-11-22-18/h2-9,13,18,20-21H,10-12H2,1H3/t13?,18-/m1/s1
PubChem CID	68325581
ChEMBL	CHEMBL3701969
IUPHAR	N/A
BindingDB	129428
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	523.5 nM	, None	BindingDB,ChEMBL

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