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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3641748
Molecular formula	C15H15F3N4O
IUPAC name	N-[4-[(2R)-morpholin-2-yl]phenyl]-6-(trifluoromethyl)pyrimidin-4-amine
Molecular weight	324.307
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.0
Synonyms	BDBM129556 SCHEMBL12609910 US8802673, 198
Inchi Key	JEHYPKCRWDQPBT-LBPRGKRZSA-N
Inchi ID	InChI=1S/C15H15F3N4O/c16-15(17,18)13-7-14(21-9-20-13)22-11-3-1-10(2-4-11)12-8-19-5-6-23-12/h1-4,7,9,12,19H,5-6,8H2,(H,20,21,22)/t12-/m0/s1
PubChem CID	68325647
ChEMBL	CHEMBL3641748
IUPHAR	N/A
BindingDB	129556
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	41.9 nM	, None	BindingDB,ChEMBL

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