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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Succinate receptor 1
Species	Homo sapiens (Human)
Gene	SUCNR1
Synonym	succinate receptor 1 succinate receptor P2Y purinoceptor 1-like P2Y purinoceptor 1 GPR91 G-protein coupled receptor 91 G protein-coupled receptor 91 SUCNR1 [ Show all ]
Disease	N/A
Length	334
Amino acid sequence	MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK
UniProt	Q9BXA5
Protein Data Bank	N/A
GPCR-HGmod model	Q9BXA5
3D structure model	This predicted structure model is from GPCR-EXP Q9BXA5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2150838
IUPHAR	166
DrugBank	BE0002258

Ligand

Name	CHEMBL2153593
Molecular formula	C20H17ClN4O
IUPAC name	2-(4-chlorophenyl)-5-[4-(1,8-naphthyridin-2-yl)butyl]-1,3,4-oxadiazole
Molecular weight	364.833
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.6
Synonyms	BDBM50393155
Inchi Key	JCFJKQLQKRHRNS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H17ClN4O/c21-16-10-7-15(8-11-16)20-25-24-18(26-20)6-2-1-5-17-12-9-14-4-3-13-22-19(14)23-17/h3-4,7-13H,1-2,5-6H2
PubChem CID	71451317
ChEMBL	CHEMBL2153593
IUPHAR	N/A
BindingDB	50393155
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<3000.0 nM	PMID21571530	BindingDB,ChEMBL

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