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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Delta-type opioid receptor
Species	Rattus norvegicus (Rat)
Gene	Oprd1
Synonym	opioid receptor OP1 DOR-1 DOR DOPr DOP delta receptor D-OR-1 Opioid receptor A [ Show all ]
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
UniProt	P33533
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL269
IUPHAR	317
DrugBank	N/A

Ligand

Name	CHEMBL2402930
Molecular formula	C32H43N9O6
IUPAC name	(5S,8S,14R)-14-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-8-benzyl-7,10,13-trioxo-2-piperidin-1-yl-1,3,6,9,12-pentazacyclopentadec-2-ene-5-carboxamide
Molecular weight	649.753
Hydrogen bond acceptor	8
Hydrogen bond donor	8
XlogP	-0.8
Synonyms	N/A
Inchi Key	AUFPKYMBJJTQQY-ASDGIDEWSA-N
Inchi ID	InChI=1S/C32H43N9O6/c33-23(15-21-9-11-22(42)12-10-21)29(45)40-26-18-37-32(41-13-5-2-6-14-41)36-17-25(28(34)44)39-31(47)24(16-20-7-3-1-4-8-20)38-27(43)19-35-30(26)46/h1,3-4,7-12,23-26,42H,2,5-6,13-19,33H2,(H2,34,44)(H,35,46)(H,36,37)(H,38,43)(H,39,47)(H,40,45)/t23-,24-,25-,26+/m0/s1
PubChem CID	71761638
ChEMBL	CHEMBL2402930
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1513.56 nM	PMID23822516	ChEMBL
IC50	4786.3 nM	PMID23822516	ChEMBL
IC50	4897.79 nM	PMID23822516	ChEMBL
Ki	1097.0 nM	PMID23822516	ChEMBL
Ki	3504.0 nM	PMID23822516	ChEMBL
Ki	3591.0 nM	PMID23822516	ChEMBL

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