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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 1
Species	Meleagris gallopavo (Wild turkey)
Gene	P2RY1
Synonym	6H1 orphan receptor ADP receptor P2Y1 Purinergic receptor
Disease	N/A for non-human GPCRs
Length	362
Amino acid sequence	MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProt	P49652
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5720
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL54116
Molecular formula	C11H17N5O9P2
IUPAC name	[2-[6-(methylamino)purin-9-yl]-5-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate
Molecular weight	425.231
Hydrogen bond acceptor	13
Hydrogen bond donor	5
XlogP	-3.0
Synonyms	BDBM50062291 Phosphoric acid mono-[2-(6-methylamino-purin-9-yl)-5-phosphonooxymethyl-tetrahydro-furan-3-yl] ester
Inchi Key	IZSBZSQDVKIOPM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H17N5O9P2/c1-12-9-8-10(14-4-13-9)16(5-15-8)11-7(25-27(20,21)22)2-6(24-11)3-23-26(17,18)19/h4-7,11H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)
PubChem CID	44299183
ChEMBL	CHEMBL54116
IUPHAR	N/A
BindingDB	50062291
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
IC50	324.0 nM	PMID9457242	BindingDB,ChEMBL
Max increase	13.0 %	PMID9457242	ChEMBL
Max inhibition	90.0 %	PMID9457242	ChEMBL

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