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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Canis lupus familiaris (Dog)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MDPLNLSWYDDDLESQNWSRPFNGSEGKPGKPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTERSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTADSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCECNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	Q9GJU1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2703
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL39669
Molecular formula	C22H30ClN3O3
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(2-hydroxy-3-phenylpropoxy)benzamide
Molecular weight	419.95
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.0
Synonyms	BDBM50023839 SCHEMBL9777180 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-3-phenyl-propoxy)-benzamide
Inchi Key	IYRYTQPCNJFYCL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H30ClN3O3/c1-3-26(4-2)11-10-25-22(28)18-13-19(23)20(24)14-21(18)29-15-17(27)12-16-8-6-5-7-9-16/h5-9,13-14,17,27H,3-4,10-12,15,24H2,1-2H3,(H,25,28)
PubChem CID	14116919
ChEMBL	CHEMBL39669
IUPHAR	N/A
BindingDB	50023839
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	<3.0 mg.kg-1	PMID3397992	ChEMBL

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