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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Mus musculus (Mouse)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
UniProt	P30557
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4336
IUPHAR	342
DrugBank	N/A

Ligand

Name	acrylic acid derivative, 17
Molecular formula	C28H24O4
IUPAC name	(E)-3-[2-(2-naphthalen-2-ylethoxy)-4-phenylmethoxyphenyl]prop-2-enoic acid
Molecular weight	424.496
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.5
Synonyms	SCHEMBL2985153 CHEMBL603625 BDBM35860 SCHEMBL2985152
Inchi Key	IXFAJVJBLAGTDS-FYWRMAATSA-N
Inchi ID	InChI=1S/C28H24O4/c29-28(30)15-13-24-12-14-26(32-20-22-6-2-1-3-7-22)19-27(24)31-17-16-21-10-11-23-8-4-5-9-25(23)18-21/h1-15,18-19H,16-17,20H2,(H,29,30)/b15-13+
PubChem CID	23016719
ChEMBL	CHEMBL603625
IUPHAR	N/A
BindingDB	35860
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1500.0 nM	PMID19700331	BindingDB
IC50	1500.0 nM	PMID19700331	ChEMBL
Ki	850.0 nM	PMID19700331	BindingDB,ChEMBL

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