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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3641755
Molecular formula	C14H15ClN4O
IUPAC name	5-chloro-N-[4-[(2R)-morpholin-2-yl]phenyl]pyrazin-2-amine
Molecular weight	290.751
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.6
Synonyms	SCHEMBL12610319 US8802673, 205 BDBM129563
Inchi Key	ATWQTXOBMPMHMO-LBPRGKRZSA-N
Inchi ID	InChI=1S/C14H15ClN4O/c15-13-8-18-14(9-17-13)19-11-3-1-10(2-4-11)12-7-16-5-6-20-12/h1-4,8-9,12,16H,5-7H2,(H,18,19)/t12-/m0/s1
PubChem CID	86766845
ChEMBL	CHEMBL3641755
IUPHAR	N/A
BindingDB	129563
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2.6 nM	, None	BindingDB,ChEMBL

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