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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	CHEMBL3641730
Molecular formula	C15H17ClN4O2
IUPAC name	4-chloro-6-methoxy-N-[4-[(2R)-morpholin-2-yl]phenyl]pyrimidin-2-amine
Molecular weight	320.777
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.4
Synonyms	SCHEMBL12609985 US8802673, 180 BDBM129538
Inchi Key	IRVWWOUMOANUBX-LBPRGKRZSA-N
Inchi ID	InChI=1S/C15H17ClN4O2/c1-21-14-8-13(16)19-15(20-14)18-11-4-2-10(3-5-11)12-9-17-6-7-22-12/h2-5,8,12,17H,6-7,9H2,1H3,(H,18,19,20)/t12-/m0/s1
PubChem CID	86766842
ChEMBL	CHEMBL3641730
IUPHAR	N/A
BindingDB	129538
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5.8 nM	, None	BindingDB,ChEMBL

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