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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M1
Species	Rattus norvegicus (Rat)
Gene	Chrm1
Synonym	cholinergic receptor, muscarinic 1 cholinergic receptor, muscarinic 1, CNS cholinergic receptor M1 muscarinic acetylcholine receptor M1 receptor M1R Chrm-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	460
Amino acid sequence	MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
UniProt	P08482
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL276
IUPHAR	13
DrugBank	N/A

Ligand

Name	CHEMBL11497
Molecular formula	C29H30F3NO
IUPAC name	3-[bis(4-fluorophenyl)methoxy]-8-[3-(4-fluorophenyl)propyl]-8-azabicyclo[3.2.1]octane
Molecular weight	465.56
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	7.1
Synonyms	BDBM50061876 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-[3-(4-fluoro-phenyl)-propyl]-8-aza-bicyclo[3.2.1]octane
Inchi Key	ASVOPIHWZMGHBA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H30F3NO/c30-23-9-3-20(4-10-23)2-1-17-33-26-15-16-27(33)19-28(18-26)34-29(21-5-11-24(31)12-6-21)22-7-13-25(32)14-8-22/h3-14,26-29H,1-2,15-19H2
PubChem CID	44267781
ChEMBL	CHEMBL11497
IUPHAR	N/A
BindingDB	50061876
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	686.0 nM	PMID10737741	BindingDB,ChEMBL

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