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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Muscarinic acetylcholine receptor DM1
Species	Drosophila melanogaster (Fruit fly)
Gene	mAChR-A
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	805
Amino acid sequence	MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCKWHTRNREGMVRGVYN
UniProt	P16395
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2366467
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	5-METHYLFURMETHIODIDE
Molecular formula	C9H16INO
IUPAC name	trimethyl-[(5-methylfuran-2-yl)methyl]azanium;iodide
Molecular weight	281.137
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	None
Synonyms	14172-53-3 Ammonium, (5-methylfurfuryl)trimethyl-, iodide CTK8C6902 Methylfurmethide iodide NSC 34095 trimethyl[(5-methylfuran-2-yl)methyl]azanium iodide 2-Furanmethanaminium, N,N,N,5-tetramethyl-, iodide (9CI) A804354 C-17681 HMS3266O10 MolPort-003-666-509 Preparation 7070 (5-Methylfurfuryl)trimethylammonium iodide 5 MFT AI3-61538 MCULE-9861159017 NCGC00095314-01 trimethyl-[(5-methyl-2-furanyl)methyl]ammonium iodide 14172-53-3 (Parent) 5-Methylfurmithide Ammonium, trimethyl(5-methylfurfuryl)-, iodide FCH1330365 Methylfurmetide NSC-34095 VZ30488 2-Furanmethanaminium,N,N,N,5-tetramethyl-, iodide (1:1) AC1L2F9Y C9H16INO J-004196 N,N,N,5-Tetramethyl-2-furanmethanaminium iodide SR-01000597917 1197-60-0 5-Methylfurfuryltrimethylammonium iodide AKOS024319033 CHEMBL1316369 Methylfurmethide NS-04617 trimethyl-[(5-methylfuran-2-yl)methyl]azanium iodide 2-Furanmethanaminium, N,N,N,5-tetramethyl-, iodide 5-Methylfurtrethonium iodide B6363 FT-0633466 Methylfutrethonium iodide NSC34095 2-Furanmethaniminium, N,N,N,5-tetramethyl-, iodide AC1Q1TMK C9H16NO.I LS-18664 N,N,N-Trimethyl-1-(5-methylfuran-2-yl)methanaminium iodide SR-01000597917-1 (5-Methyl-2-furyl)methyltrimethylammonium iodide [ Show all ]
Inchi Key	IHTCZSNKQINGDD-UHFFFAOYSA-M
Inchi ID	InChI=1S/C9H16NO.HI/c1-8-5-6-9(11-8)7-10(2,3)4;/h5-6H,7H2,1-4H3;1H/q+1;/p-1
PubChem CID	70973
ChEMBL	CHEMBL1316369
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	12300.0 nM	PMID17319687	ChEMBL
Ki	14900.0 nM	PMID17319687	ChEMBL

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