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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 1
Species	Meleagris gallopavo (Wild turkey)
Gene	P2RY1
Synonym	6H1 orphan receptor ADP receptor P2Y1 Purinergic receptor
Disease	N/A for non-human GPCRs
Length	362
Amino acid sequence	MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProt	P49652
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5720
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL355406
Molecular formula	C12H20N6O8P2
IUPAC name	[(1R,2R,4R)-4-[2-amino-6-(methylamino)purin-9-yl]-2-phosphonooxycyclopentyl]methyl dihydrogen phosphate
Molecular weight	438.274
Hydrogen bond acceptor	13
Hydrogen bond donor	6
XlogP	-2.8
Synonyms	BDBM50085829 Phosphoric acid mono-[4-(2-amino-6-methylamino-purin-9-yl)-2-phosphonooxy-cyclopentyl] ester
Inchi Key	IHQMVABLPLRMMJ-BWZBUEFSSA-N
Inchi ID	InChI=1S/C12H20N6O8P2/c1-14-10-9-11(17-12(13)16-10)18(5-15-9)7-2-6(4-25-27(19,20)21)8(3-7)26-28(22,23)24/h5-8H,2-4H2,1H3,(H2,19,20,21)(H2,22,23,24)(H3,13,14,16,17)/t6-,7-,8-/m1/s1
PubChem CID	44380922
ChEMBL	CHEMBL355406
IUPHAR	N/A
BindingDB	50085829
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
EC50	6510.0 nM	PMID10715151	BindingDB,ChEMBL
IC50	5420.0 nM	PMID10715151	BindingDB,ChEMBL
Max increase	26.0 %	PMID10715151	ChEMBL
Max inhibition	74.0 %	PMID10715151	ChEMBL

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