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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Taste receptor type 2 member 31
Species	Homo sapiens (Human)
Gene	TAS2R31
Synonym	taste receptor, type 2, member 31 Taste receptor type 2 member 53 Taste receptor type 2 member 44 TAS2R44 TAS2R31 T2R53 T2R44 T2R31 taste receptor, type 2, member 44 [ Show all ]
Disease	N/A
Length	309
Amino acid sequence	MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
UniProt	P59538
Protein Data Bank	N/A
GPCR-HGmod model	P59538
3D structure model	This predicted structure model is from GPCR-EXP P59538.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2034804
IUPHAR	674
DrugBank	N/A

Ligand

Name	4'-Isobutyrylhomoeriodictyol
Molecular formula	C20H20O7
IUPAC name	[4-[(2S)-5,7-dihydroxy-4-oxo-2,3-dihydrochromen-2-yl]-2-methoxyphenyl] 2-methylpropanoate
Molecular weight	372.373
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.5
Synonyms	CHEMBL490162 BDBM50384791
Inchi Key	IGCZWOGVHOOOEO-INIZCTEOSA-N
Inchi ID	InChI=1S/C20H20O7/c1-10(2)20(24)27-15-5-4-11(6-17(15)25-3)16-9-14(23)19-13(22)7-12(21)8-18(19)26-16/h4-8,10,16,21-22H,9H2,1-3H3/t16-/m0/s1
PubChem CID	44576022
ChEMBL	CHEMBL490162
IUPHAR	N/A
BindingDB	50384791
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2000.0 nM	PMID21650152	BindingDB,ChEMBL

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