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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M1
Species	Rattus norvegicus (Rat)
Gene	Chrm1
Synonym	cholinergic receptor, muscarinic 1 cholinergic receptor, muscarinic 1, CNS cholinergic receptor M1 muscarinic acetylcholine receptor M1 receptor M1R Chrm-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	460
Amino acid sequence	MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
UniProt	P08482
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL276
IUPHAR	13
DrugBank	N/A

Ligand

Name	(S)-2-Amino-3-chloropropanoic acid
Molecular formula	C3H6ClNO2
IUPAC name	(2S)-2-amino-3-chloropropanoic acid
Molecular weight	123.536
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	-2.8
Synonyms	AC1L980E C2N KB-211130 .beta.-CDA AKOS006283078 CHEMBL295666 NCGC00015282-01 ST2402779 (2S)-2-amino-3-chloro-propanoic acid 39217-38-4 beta-Chloro-D-alanine DS-6740 (S)-2-Amino-3-chloropropionic Acid AJ-26603 CHEBI:17092 Lopac-C-9033 2-AMINO-3-CHLORO-PROPANOIC ACID ASBJGPTTYPEMLP-UWTATZPHSA-N CTK1C6529 SC-98225 ZINC1529479 (2S)-2-Amino-3-chloropropanoic acid 5119AB C02634 FCH837289 (S)-3-chloroalanine AK122809 MolPort-027-837-061 3-chloro-D-alanine AX8246987 D-Alanine, 3-chloro- SCHEMBL896870 [ Show all ]
Inchi Key	ASBJGPTTYPEMLP-UWTATZPHSA-N
Inchi ID	InChI=1S/C3H6ClNO2/c4-1-2(5)3(6)7/h2H,1,5H2,(H,6,7)/t2-/m1/s1
PubChem CID	439771
ChEMBL	CHEMBL295666
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Potency	12589.3 nM	PubChem BioAssay data set	ChEMBL

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