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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H1 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH1
Synonym	H1R HH1R
Disease	N/A for non-human GPCRs
Length	488
Amino acid sequence	MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFPITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGCIMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTFKRILRIPP
UniProt	P31389
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3943
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2262480
Molecular formula	C12H17N3O2
IUPAC name	2-(1H-benzimidazol-2-ylmethylamino)-2-methylpropane-1,3-diol
Molecular weight	235.287
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	-0.2
Synonyms	N/A
Inchi Key	ABXSYRUREXINDQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H17N3O2/c1-12(7-16,8-17)13-6-11-14-9-4-2-3-5-10(9)15-11/h2-5,13,16-17H,6-8H2,1H3,(H,14,15)
PubChem CID	76315756
ChEMBL	CHEMBL2262480
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Emax	14.2 %	Med Chem Res, (2009) 18:3:187	ChEMBL
Inhibition	0.0 %	Med Chem Res, (2009) 18:3:187	ChEMBL
Inhibition	11.2 %	Med Chem Res, (2009) 18:3:187	ChEMBL
Inhibition	14.2 %	Med Chem Res, (2009) 18:3:187	ChEMBL
Inhibition	50.0 %	Med Chem Res, (2009) 18:3:187	ChEMBL
Inhibition	85.7 %	Med Chem Res, (2009) 18:3:187	ChEMBL

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