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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1831997
Molecular formula	C12H13F3N2O3
IUPAC name	(4S)-4-[2-[3-(trifluoromethoxy)phenoxy]ethyl]-4,5-dihydro-1,3-oxazol-2-amine
Molecular weight	290.242
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.5
Synonyms	US8729113, 19 CHEMBL3652699 BDBM122309
Inchi Key	ARHKWSCPQQSWOQ-QMMMGPOBSA-N
Inchi ID	InChI=1S/C12H13F3N2O3/c13-12(14,15)20-10-3-1-2-9(6-10)18-5-4-8-7-19-11(16)17-8/h1-3,6,8H,4-5,7H2,(H2,16,17)/t8-/m0/s1
PubChem CID	45102308
ChEMBL	CHEMBL3652699
IUPHAR	N/A
BindingDB	122309
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2.1 nM	, None	BindingDB,ChEMBL

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