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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Mus musculus (Mouse)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
UniProt	P30557
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4336
IUPHAR	342
DrugBank	N/A

Ligand

Name	CHEMBL602337
Molecular formula	C28H31NO4
IUPAC name	3-[2-[(3-methyl-1-phenylbutyl)carbamoyl]-4-(phenoxymethyl)phenyl]propanoic acid
Molecular weight	445.559
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.6
Synonyms	3-(2-(3-methyl-1-phenylbutylcarbamoyl)-4-(phenoxymethyl)phenyl)propanoic acid BDBM50307409 SCHEMBL2978901 3-[2-{[(3-Methyl-1-phenylbutyl)amino]carbonyl}-4-(phenoxymethyl)phenyl]propanoic acid
Inchi Key	HSHFSMZZWDOMPK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31NO4/c1-20(2)17-26(23-9-5-3-6-10-23)29-28(32)25-18-21(13-14-22(25)15-16-27(30)31)19-33-24-11-7-4-8-12-24/h3-14,18,20,26H,15-17,19H2,1-2H3,(H,29,32)(H,30,31)
PubChem CID	23017731
ChEMBL	CHEMBL602337
IUPHAR	N/A
BindingDB	50307409
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	68.0 nM	PMID20004584, PMID20129791	BindingDB,ChEMBL
Ki	0.7 nM	PMID20004584, PMID20129791	BindingDB,ChEMBL

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