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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Bos taurus (Bovine)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKEAINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKDNLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
UniProt	Q28044
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3373
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	pronethalol
Molecular formula	C15H19NO
IUPAC name	1-naphthalen-2-yl-2-(propan-2-ylamino)ethanol
Molecular weight	229.323
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	3.0
Synonyms	DSSTox_GSID_21193 ICI 38,174 KBio2_007068 NCGC00024809-04 Prestwick1_000974 (2-Naphthyl)-1-isopropylaminoethanol Pronetalolum 2-NAPHTHALENEMETHANOL, alpha-((ISOPROPYLAMINO)METHYL)- Spectrum3_000969 AC1Q776Q BDBM25760 CCRIS 9216 FT-0674051 IDI1_000930 KBioSS_001932 Neathalide Pronetalol 2-(isopropylamino)-1-(2-naphthyl)ethanol SBI-0051834.P002 54-80-8 Spectrum_001452 AN-51024 BRD-A87715314-003-09-4 CHEMBL16476 DivK1c_000930 HRSANNODOVBCST-UHFFFAOYSA-N KBio2_001932 NCGC00024809-02 NINDS_000930 (+/-)-1-(2'-Naphthyl)-2-isopropylaminoethanol Pronetalolo 2-Naphthalenemethanol, .alpha.-[[(1-methylethyl)amino]methyl]- SPBio_002918 AB00053671_08 AY 6204 [AS HYDROCHLORIDE] C11707 DSSTox_RID_76003 ICI 38174 [AS HYDROCHLORIDE] KBio3_001797 NCGC00024809-05 Prestwick2_000974 1-(naphthalen-2-yl)-2-(propan-2-ylamino)ethan-1-ol Pronetalolum [INN-Latin] 2-[(1-methylethyl)amino]-1-naphthalen-2-ylethanol Spectrum4_001089 AKOS010125625 BPBio1_001109 CHEBI:8463 Compound 38174 GNF-Pf-2670 Inetol LS-7672 NETH ( -)-Pronethalol Pronetalol [INN:BAN] 2-(isopropylamino)-1-(naphthalen-2-yl)ethanol SCHEMBL78996 AB00053671 Tox21_110927 AOB5347 BSPBio_001007 DSSTox_CID_1193 HY-B1238 KBio2_004500 NCGC00024809-03 Prestwick0_000974 (+/-)-Pronethalol Pronetalolo [DCIT] 2-Naphthalenemethanol, alpha-(((1-methylethyl)amino)methyl)- Spectrum2_001570 AC1L1J98 AY-6204 HCl CAS-54-80-8 DTXSID8021193 ICI-38174 [As Hydrochloride] KBioGR_001478 NCGC00024809-07 Prestwick3_000974 1-naphthalen-2-yl-2-(propan-2-ylamino)ethanol Spectrum5_001165 Alderlin BRD-A87715314-003-05-2 CS-4884 HMS2089K07 KBio1_000930 Naphthylisoproterenol Nethalide (+-)-Pronethalol Pronetalol [INN] 2-Isopropylamino-1-(naphth-2-yl)ethanol SPBio_001480 AB00053671-07 Tox21_110927_1 AS-16864 BSPBio_002577 [ Show all ]
Inchi Key	HRSANNODOVBCST-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H19NO/c1-11(2)16-10-15(17)14-8-7-12-5-3-4-6-13(12)9-14/h3-9,11,15-17H,10H2,1-2H3
PubChem CID	4930
ChEMBL	CHEMBL16476
IUPHAR	N/A
BindingDB	25760
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
-Delta G	10.07 -	PMID2836587	ChEMBL
-Log KD	7.1 -	PMID2993621	ChEMBL
Kd	160.0 nM	PMID2993621	BindingDB,ChEMBL

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